Emdogain and Perio Surgery

emdogainEmdogain, also known as Enamel Matrix Derivative (EMD), is a regenerative material used in periodontal (gum) treatment to promote the regeneration of periodontal tissues, including cementum, periodontal ligament, and alveolar bone. It’s derived from the enamel matrix proteins of developing porcine (pig) teeth.

How Emdogain Works

Emdogain works by mimicking the natural signals that guide tooth development during embryogenesis. When applied to the affected area, it encourages the regeneration of the tissues that support the teeth. It stimulates the attachment of periodontal ligament cells to the tooth root surface, promotes the formation of new cementum, and can help restore lost bone structure.


Emdogain is primarily used in periodontal procedures, including:

  • Treatment of Periodontal Defects: Emdogain is applied to periodontal defects caused by gum disease or other factors. It aids in the regeneration of tissues lost due to periodontitis, improving the overall health of the affected area.
  • Guided Tissue Regeneration (GTR): Emdogain can be used in conjunction with barrier membranes to guide the regeneration of periodontal tissues in cases of more extensive defects.
  • Gingival Recession Treatment: Emdogain can also be used to treat gingival recession by promoting the regeneration of the gingival tissues that have receded.

Benefits of Emdogain

  • Tissue Regeneration: Emdogain is specifically designed to promote the regeneration of periodontal tissues, leading to improved attachment of teeth and better gum health.
  • Natural Approach: It utilizes the body’s natural regenerative processes to restore lost tissues, providing a more biologically driven solution.
  • Predictable Outcomes: Emdogain has shown consistent and predictable results in various clinical studies.


Emdogain is generally well-tolerated, but as with any dental material or treatment, there may be individual variations in response. Dentists and periodontists with training and experience in using Emdogain can provide the best advice on whether it’s suitable for a patient’s specific needs.

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